Starter Grants for Clinical Lecturers

Simon Abram, Leveraging Routinely Collected Big Data to Benchmark and Improve Surgical Care Outcomes

Simon Bell, Understanding the role of Hexokinase 1 deficiency as a contributor to the cellular pathology of Alzheimer’s Disease.

Alison Berner, Genomic Origins Of Sex-bias in Colorectal Cancer Epidemiology (GOOSCCE)

Simon Biddie, Uncovering functional host non-coding genetic variants associated with risk of severe COVID-19 using high-throughput screening

Matthew Clarke, The classification and characterisation of high-grade gliomas in teenagers and young adults

Helen Devine, Is there dysfunction at the neuromuscular junction in spinal bulbar muscular atrophy which can be a future target for therapeutic intervention in SBMA and other motor neuron diseases?

Sarah Dorrington, Mental health and occupational outcomes of people accessing an early pregnancy unit (EPAU) in south London: an eLIXIR data linkage study

Alexander Fletcher, Non-invasive molecular imaging to measure fibroblast activation in right ventricular disease

Amanda Goodwin, Understanding how mesenchymal G protein signalling controls lung development and repair

Robert Hyde, The automated diagnosis of disease using machine vision: lameness in dairy cattle

Theresa Hydes, Patient preferences for the delivery of the non-alcoholic fatty liver disease clinical pathway: let’s move towards patient-centered care

Miriam Manook, Systems serology in transplantation: comprehensive profiling of HLA antibodies to stratify immunological risk

Chris Miles, Utility of the high-lead ECG configuration during exercise stress testing in Brugada syndrome

Hannah Nieto, FNA-seq: Nanopore sequencing of fine needle aspirate samples to revolutionise the diagnosis and treatment of thyroid cancer

Karl Payne, COMBined Blood And Tissue prediction for immunotherapy response in recurrent/metastatic Head and Neck Squamous Cell Carcinoma (COMBAT HNSCC)

Laurence Pearmain, Resolving  monocyte-derived macrophage extracellular matrix crosstalk within the fibrotic niche for precision biomarker guided therapies in Idiopathic Pulmonary Fibrosis.

Adam Pennycuick, Parallelised Cancer Therapy based on Copy Number Targeting

Haseeb Rahman, Improving diagnosis and outcomes of Coronary Microvascular Dysfunction by applying a network approach across the UK

Sayyid Raza, Understanding the role of Neuron Navigator 3 in kidney fibrosis

Akshay Shah, Inflammatory phenotypes, haemoglobin recovery and economic evaluation of treating anaemia in survivors of critical illness

Bo Sun, Transcriptomic profiling of autoantibody-mediated neuronal perturbations in CASPR2-antibody encephalitis

Joshua Totty, First-in-man clinical trial investigating the effect of hair cycle modulation on wound healing.

Lucy Whitaker, Improving understanding of endometriosis pain flares to support patients with self-management and prevention (EndoFLARE): a feasibility study

Yanushi Wijeyeratne, Polygenic association study of risk and phenotype in SCN5A-E1784K families

Adam Al-Diwani, University of Oxford, Cervical lymph node aspirations: cellular and molecular phenotyping at an emerging neuro-immune nexus

Rubika Balendra, University College London, Investigating mechanisms of RNA dysregulation in C9orf72-associated motor neuron disease and frontotemporal dementia

Lucy Beishon, University of Leicester, Vascular mEchanismS in, dePression, dementiA, and deliRum: The VESPAR project

Floryne Buishand, Royal Veterinary College, University of London, Identification of novel druggable targets in canine insulinoma through single-cell transcriptomic analysis

Nicholas Cunniffe, University of Cambridge, Examining the long-term effects of the combination of metformin and clemastine on remyelination and neuroprotection; a follow-up study of the Cambridge Centre for Myelin Repair trial Two

Adam Dale, University of Southampton,
Characterising human CD4+ effector T cell responses following experimentally-induced colonisation with genetically-modified Neisseria lactamica expressing the meningococcal vaccine antigen, Neisseria adhesin A.

Kate Duhig, University of Manchester, Developing MRI sequences to Assess maternal cardiac and Placental function in women with HyperteNsion in prEgnancy (DAPHNE)

Laura Goodfellow, University of Liverpool,
Are yeasts the missing link between the vaginal bacteria and preterm birth?

Dermot Linden, Queen's University Belfast, Epstein-Barr Virus suppression in Chronic Obstructive Pulmonary Disease (EViSCO): A mechanistic study to evaluate the sputum transcriptome and microbiome in moderate-to-severe COPD

Johnathan Millar, University of Edinburgh,
Functional genomics and ARDS: in-silico and in-vitro gene editing to dissect genome wide associations in patients with Acute Respiratory Distress Syndrome

Camus Nimmo, Francis Crick Institute,
Targeted mutagenesis to identify resistance conferring mutations for new drugs for Mycobacterium tuberculosis

Emma Rose McGlone, Imperial College London, Hepatic glucagon sensitivity before and after bariatric surgery: use of a plasma biomarker to predict resolution of metabolic-associated liver disease

Michaela Reichmann, University of Southampton, Multidimensional transcriptomic analysis of tuberculosis granulomas to define pathophysiological mechanisms

Ola Rominiyi, University of Sheffield, High-grade glioma treatment design through mapping spatial differences in the DNA damage response of cancer stem cells

Neil Ryan, University of Bristol, MicrosatEllite Womb Surveillance (MEWS) study

Yazan Sulaiman Khaled, University of Leeds, Developing a novel theranostic nanoparticle for precision surgery in pancreatic cancer

Eugene Tang, Newcastle University,
The Impact of Cognitive Difficulties On Post-Stroke Recovery

Wendy Thompson, University of Manchester, Developing ways to evaluate process during the clinical trial of a dental antibiotic stewardship intervention

Oliver Todd, University of Leeds, Stratified hypertension management in later life: establishment of cohort linkage between ambulatory blood pressure measurements and routine health and social care data in Connected Bradford

Tabitha Turner-Stokes, Imperial College London, From human genetics to monocyte-specific disease mechanisms in systemic lupus erythematosus

Yize Wan, Queen Mary University of London, Acute illness as a driver of long-term disease and health inequality across socioeconomic and ethnic groups

Hannah Woodcock, University of Cambridge, Investigating lung epithelial progenitor cell fate in the developing human lung

Kathryn Allan, University of Glasgow, Investigating the impact of Coxiella burnetii infection on dairy cattle in Scotland.

Emily Bowen, University of Bristol, Investigating Shiga toxin-induced endothelial glycocalyx dysfunction as a potential therapeutic target in Haemolytic Uraemic Syndrome

Mitchell Chen, Imperial College London, Deep Learning and Radiomics-based Cardiovascular Disease Assessment on Ungated Contrast Enhanced Computed Tomography and its Integration in a Clinical Predictive Model for Patients with Non-Small Cell Lung Cancer

Radoslaw Debiec, University of Leicester, Bicuspid aorRtic vAlVe gEnetic research – tHoracic aortic 18F-fluoridE microcAlcification to monitoR aorTopathy (BRAVE-HEART substudy)

Lydia Finney, Imperial College London, Investigating the role of specialist pro-resolving mediators in viral exacerbations of chronic obstructive pulmonary disease

Daniel Fudulu, University of Bristol, Metabolomoics and clinical based predictive modles for acute kidney injury after coronary atery bypass grafting

Rebecca Gosling, University of Sheffield, Comprehensive modelling of myocardial ischaemic bur

Timothy Hardy, Newcastle University, Characterisation of somatic mutation analysis in cell free DNA of patients with Non Alcoholic Fatty Liver Disease

Jamilla Hussain, Hull & York Medical School, Health inequalities related to ethnicity and socio-economic position at the end-of-life

David Hutchings, University of Manchester, Why is lamin cardiomyopathy a perfect storm for arrhythmias?

Eleni Louka, University of Oxford, Investigating the mechanisms of relapse in Juvenile Myelomonocytic Leukaemia (JMML)

Imran Noorani, Francis Crick Institute, Defining the molecular impact of extrachromosomal oncogenes on cellular interactions in the glioblastoma microenvironment

Majd Protty, Cardiff Univeristy, Investigating the role of procoagulant enzymatically oxidized phospholipids in arterial thrombosis using in vivo models

Mahim Qureshi, University of Bristol, Composite primary endpoints for randomised controlled trials of invasive and surgical procedures

Rebecca Spencer, University of Leeds, Circulating placental extracellular vesicles as non-invasive placental biopsies and sources of diagnostic markers in fetal growth restriction

Tathyane Teshima, University College London, Identifying the cellular and genetic profile of salivary gland damage in Sjogren’s Syndrome with focus on how specific tissues influence disease at single-cell level

Ganesh Vigneswaran, University of Southampton, Machine learning to identify predictors of outcome and survival in the treatment of mUM (metastatic uveal melanoma) with M-PHP (melphalan percutaneous hepatic perfusion)

Akira Wiberg, University of Oxford, Developing a single cell atlas of the median nerve microenvironment in the carpal tunnel

Anam Anzark, Queen Mary University of London, Investigating a role of seizures in promoting progression of Glioblastoma Multiforme 

Damiano Giuseppe Barone, University of Cambridge School of Clinical medicine, Minimally Invasive Spinal Cord Stimulation for chronic pain

Andrew Bell, University of Glasgow, The role of distinct populations of spinal excitatory interneurons in post-operative pain

Camilla Clark, St George's University Hospitals NHS, How we understand our emotions: Is alexithymia following traumatic brain injury a generalised failure of interoception?

Jonathan Evans, University of Exeter Medical School, Cross-Cultural Validation and Calibration of the PROMIS

Michael FitzPatrick, University of Oxford, Elucidating functional and spatial characteristics of CD8+ T cell populations in coeliac disease

Anne-Lise Goddings, University College London, The association between glycaemic control in young people with Type 1 diabetes mellitus and executive functioning in social contexts: a pilot study 

Ankur Gupta-Wright, University College London, Improving diagnosis of presumptive TB in hospitalised patients in Malawi 

Neil Halliday, University College London, Assessment of Treg function, CD28 costimulation and immune dysregulation in autoimmune liver diseases

James Howard, Imperial College London, Diastolic function assessment with cardiac magnetic resonance imaging and echocardiography: a scan-rescan study

Thomas Massey, Cardiff University, Using genetic modifiers to investigate the molecular mechanisms of repeat expansion in Huntington’s disease

James Masters, University of Oxford, Collecting Data on hip fracture surgery in sub-saharan africa (Hip fracturE surGery In sub-sahaRan Africa-HEGIRA)

Susanna Mills, Newcastle University, Mixed-methods study to generate evidence to inform weight management interventions in adult secure care mental health inpatient settings

Sophie Patterson, University of Lancaster, Expansion of Remote Contraceptive Services in England: Implications for Inequalities in Women’s Reproductive Health 

Helen Payne, Imperial College London, Prevalence of cytomeglaovirus and Epstein Barr virus and associated immune-activation and inflammation in adolescents with perinatally-acquired HIV

Muhammad Rashid, Keele University School of Medicine, REadmissions, Adverse Complications and ouTcomes following Acute Myocardial Infarction (REACT-AMI) study

Jennifer Rayner, University of Oxford, Mapping complete energetic pathways in the human heart using magnetic resonance spectroscopy

Maria Rogdaki, King's College London, Determining the molecular mechanisms of psychosis and developing a cellular platform for novel drug discovery: From brain to cell and back again

Jakub Scaber, University of Oxford, Investigating selective vulnerability in C9orf72 positive amyotrophic lateral sclerosis using induced pluripotent stem cell derived motor and sensory neurons

Charlotte-Eve Short, Imperial College London, The immunological basis for increased Preterm Birth in HIV-1 infected pregnant women and the influence of different classes of antiretroviral therapy

Norman Shreeve, University of Cambridge School of Clinical Medicine, The fetal microglial response to glucocorticoid exposure in utero 

Nicola Tempest, University of Liverpool, Preliminary study, characterising the region-specific abnormalities in the endometrium of women with recurrent implantation failure

Stephanie Worton, University of Manchester, Investigating novel treatments for maternal vascular dysfunction in the STOX1 model of pre-eclampsia; the missing link in the translational pathway

Amir Youshani, University of Manchester, Characterisation of senescence-associated secretory phenotype in glioblastoma

Tian Zhao, University of Cambridge, The effect of low-dose interleukin-2 on atherosclerotic plaque immune cells in patients undergoing carotid endarterectomy

Sarah Al-Bachari, University of Lancaster, ENIGMA-PD-Vasc: An international multicentre analysis of cerebral vascular changes in Parkinson's disease

Nay Aung, Queen Mary University of London, Leveraging natural language processing, genomics and imaging to evaluate the determinants of adverse cardiovascular events

Thomas Cope, University of Cambridge School of Clinical Medicine, The impact of neurodegeneration on neuronal coding – 7T fMRI in frontal and temporal aphasia

Vitor de Carvalho Moreno das Neves, King's College London, Investigating periodontitis host-related factors at molecular level: healthy-to-diseased periodontium single-cell characterisation and molecular dynamics of aging

Harveer Dev, University of Cambridge, Prostate Organoids for Early disease research and Treatments (POET) study

Fatima Dhalla, University of Oxford, Identifying novel candidate genes for inborn errors of thymic stromal cells that cause severe congenital T-cell lymphopaenia

Wen Ding, University of Bristol, Progressing the Clinical Applicability of Adeno-Associated Virus Gene Therapy for Genetic Nephrotic Syndrome

Sherif Elsharkawy, King's College London, Biomineralization Of White Spot Dental Enamel Lesions Via A Protein-based Approach ‘‘KERATINAMEL’’

Nicholas Evans, University of Cambridge School of Clinical Medicine, Dual PET Evaluation of Inflammation across the Neurovascular Interface in Cerebrovascular Disease

Douglas Fink, London School of Hygiene and Tropical Medicine, Regulation of innate immunity by epigenetic control of endogenous retroelements

Jonathan Fisher, University College London, Supporting homing and longevity of gamma delta T cells for cancer immunotherapy

Iram Haq, Newcastle University, Investigating the effects of CFTR modulators on the epithelial sodium channel (ENaC) in the cystic fibrosis airway

Ann Louise Hunter, University of Manchester, Applying genomic technologies to understand adipose inflammation

Keaton Jones, University of Oxford, Macrophage repolarisation in murine pancreatic cancer

Harriet Kemp, Imperial College London, A feasibility study investigating novel longitudinal cutaneous markers of neuropathic pain

Katharine Lodge, Imperial College London, The role of hypoxia in neutrophil-mediated endothelial dysfunction: application to inflammatory lung disease

Alexander Mentzer, University of Oxford, Long range sequencing of the human immunoglobulin loci to direct early diagnostics and functional gene-antibody correlations in COVID-19 disease

Muhummad Sohaib Nazir, King's College London, Imaging guided in-vivo histological validation of cardiac sarcoid using 68Ga- DOTATATE and novel PET-MR methods

Naaventhan Palaniyappan, University of Nottingham, Repurposing Sirolimus in Cirrhosis: Assessing Response with Magnetic Resonance Imaging (MRI)

Valeria Parlatini, King's College London, Understanding the impact of the Covid-19 pandemic on the mental health of children and young people with pre-existing mental health conditions

Amit Sud, Institute of Cancer Research, Defining the genomic landscape of acute myeloid leukaemia in adults using whole genome sequencing

Oliver Van Hecke, University of Oxford, Using a child’s antibiotic history as a data-enabled brief intervention to optimise antibiotic prescribing in children with acute respiratory tract infections in general practice: a feasibility study

Paul Vulliamy, Queen Mary University of London, Platelet-mediated immunomodulation after major trauma

Emily Watts, University of Edinburgh, Dissecting the role of the mTORC/AMPK axis in neutrophil mediated lung injury

Katie Williams, King's College London, Investigation of axial length variation and myopia in health and disease

Daisy Wilson, University of Birmingham Medical School, Covid-19 model of acute sarcopenia recovery: investigating immune-muscle interactions

Bernadette Young, University of Oxford, Investigating the role of bacterial genomic adaptation in orthopaedic infection