Sarah Al-Bachari, University of Lancaster, ENIGMA-PD-Vasc: An international multicentre analysis of cerebral vascular changes in Parkinson's disease
Nay Aung, Queen Mary University of London, Leveraging natural language processing, genomics and imaging to evaluate the determinants of adverse cardiovascular events
Thomas Cope, University of Cambridge School of Clinical Medicine, The impact of neurodegeneration on neuronal coding – 7T fMRI in frontal and temporal aphasia
Vitor de Carvalho Moreno das Neves, King's College London, Investigating periodontitis host-related factors at molecular level: healthy-to-diseased periodontium single-cell characterisation and molecular dynamics of aging.
Harveer Dev, University of Cambridge, Prostate Organoids for Early disease research and Treatments (POET) study
Fatima Dhalla, University of Oxford, Identifying novel candidate genes for inborn errors of thymic stromal cells that cause severe congenital T-cell lymphopaenia
Wen Ding, University of Bristol, Progressing the Clinical Applicability of Adeno-Associated Virus Gene Therapy for Genetic Nephrotic Syndrome
Sherif Elsharkawy, King's College London, Biomineralization Of White Spot Dental Enamel Lesions Via A Protein-based Approach ‘‘KERATINAMEL’’
Nicholas Evans, University of Cambridge School of Clinical Medicine, Dual PET Evaluation of Inflammation across the Neurovascular Interface in Cerebrovascular Disease
Douglas Fink, London School of Hygiene and Tropical Medicine, Regulation of innate immunity by epigenetic control of endogenous retroelements
Jonathan Fisher, University College London, Supporting homing and longevity of gamma delta T cells for cancer immunotherapy
Iram Haq, Newcastle University, Investigating the effects of CFTR modulators on the epithelial sodium channel (ENaC) in the cystic fibrosis airway
Ann Louise Hunter, University of Manchester, Applying genomic technologies to understand adipose inflammation
Keaton Jones, University of Oxford, Macrophage repolarisation in murine pancreatic cancer.
Harriet Kemp, Imperial College London, A feasibility study investigating novel longitudinal cutaneous markers of neuropathic pain
Katharine Lodge, Imperial College London, The role of hypoxia in neutrophil-mediated endothelial dysfunction: application to inflammatory lung disease
Alexander Mentzer, University of Oxford, Long range sequencing of the human immunoglobulin loci to direct early diagnostics and functional gene-antibody correlations in COVID-19 disease.
Muhummad Sohaib Nazir, King's College London, Imaging guided in-vivo histological validation of cardiac sarcoid using 68Ga- DOTATATE and novel PET-MR methods.
Naaventhan Palaniyappan, University of Nottingham, Repurposing Sirolimus in Cirrhosis: Assessing Response with Magnetic Resonance Imaging (MRI)
Valeria Parlatini, King's College London, Understanding the impact of the Covid-19 pandemic on the mental health of children and young people with pre-existing mental health conditions.
Amit Sud, Institute of Cancer Research, Defining the genomic landscape of acute myeloid leukaemia in adults using whole genome sequencing
Oliver Van Hecke, University of Oxford, Using a child’s antibiotic history as a data-enabled brief intervention to optimise antibiotic prescribing in children with acute respiratory tract infections in general practice: a feasibility study
Paul Vulliamy, Queen Mary University of London, Platelet-mediated immunomodulation after major trauma
Emily Watts, University of Edinburgh, Dissecting the role of the mTORC/AMPK axis in neutrophil mediated lung injury
Katie Williams, King's College London, Investigation of axial length variation and myopia in health and disease
Daisy Wilson, University of Birmingham Medical School, Covid-19 model of acute sarcopenia recovery: investigating immune-muscle interactions.
Bernadette Young, University of Oxford, Investigating the role of bacterial genomic adaptation in orthopaedic infection
Sarah Aitken, University of Cambridge, The molecular pathology of liver cancer: multi-omics dissection of liver cancer in transplant patients
Matthew Booker, University of Bristol, REMote Advice for Prehospital Professionals (REMAPP): a conversation analytic study of clinical telephone advice
Anob Chakrabarti, Francis Crick Institute, Modelling regulatory mechanisms of RNP condensation in neuronal development: insights into neurodegeneration
Elizabeth Curtis, University of Southampton, Does maternal gestational vitamin D supplementation influence offspring DNA methylation in childhood?
Jim Dunham, University of Bristol, Exploration of human C-nociceptor pathophysiology
Kiterie Faller, University of Edinburgh, Fuelling Motor Neuron Diseases – A Systematic Study of Energy Metabolism in ALS and SMA.
Rebecca Geddes, Royal Veterinary College, University of London, Establishing the domestic cat as a novel model of spontaneous nephrolithiasis by investigation of the genetic basis of disease
Michael James Gilhooley, University College London, Single retinal ganglion cell transcriptomics in models of hereditary optic neuropathy
Kathryn Griffin, University of Leeds, Developing light sheet microscopy of murine and human gut to assess (pre)diabetic microvascular disease
Katharina Kohler, University of Cambridge, Data driven modelling of emergency surgical services
Emily Lees, University of Oxford, Investigating the interactions of Salmonellae with the human intestinal epithelium and macrophages
Gulraj Matharu, University of Bristol, What is the clinical effectiveness of regional anaesthesia compared with general anaesthesia for post-operative complications in patients with hip fractures?
Laura McCreight, University of Dundee School of Medicine, Using C-Peptide measurement to clarify, simplify and personalise the management of diabetes (CLASP): CLARIFY.
Robert McCutcheon, King's College London, Excitation/Inhibition Balance in Autism Spectrum Disorder and Schizophrenia: Building A Multi-Scale Understanding
Maria Prendecki, Imperial College London, The role of low density granulocytes in the pathogenesis of anti-neutrophil cytoplasm antibody associated vasculitis
Elizabeth Radford, University of Cambridge, Transforming diagnostic certainty in developmental disorders using CRISPR-based saturation genome editing
Laura Randall, University of Nottingham, Evaluating the novel use of mass-spectrometry based approaches for investigating the pathogenesis of lameness in dairy cattle
Patrick Redmond, King's College London, Development of a complex intervention to optimise safe prescribing for older people in general practice post hospitalisation
Anna Rose, University of Oxford, Development of oncolytic viruses for treatment of ATRX-deficient paediatric brain and bone tumours
Panicos Shangaris, King's College London, In Utero Therapy for the Induction of Immune Tolerance
Sanooj Soni, Imperial College London, Microvesicle-mediated signalling during acute lung injury: Defining the role of acid sphingomyelinase
Andrew Stewart, University of Cambridge School of Clinical Medicine, Investigating the cellular and microvesicle content of human urine in health and disease
Danielle Whittaker, King's College London, Investigating cerebellar GABAergic cell specification in a novel recessive syndrome with cerebellar hypoplasia and hypogonadotropic hypogonadism.
Svetislav Zaric, King's College London, Derivation and validation of microbe-associated-molecular-patterns-based biomarkers for personalised periodontal medicine
Kenneth Baker, Newcastle University, Single cell characterisation of a flare-associated CD8+ T-cell subset in patients with rheumatoid arthritis
Alaa Bani Hani, University of Leeds, Peptidic biomimetic scaffolds and silver diamine fluoride as multi-component systems for regeneration of dentine carious lesions in vitro.
Ryan Buchanan, University of Southampton, Social network facilitated engagement in people who are Homeless to address InEqualities in alcohol-related Liver Disease - The SHIELD feasibility study
Claire Connell, University of Cambridge, Targeting Systemic Metabolism to Improve Immune Function in Pancreatic Cancer Associated Cachexia
Sarah Crisp, University of Cambridge, Pathogenic mechanisms of dipeptidyl-peptidase-like protein 6 (DPPX) autoantibodies
Rima Dhillon-Smith, University of Birmingham, Investigating the fertility and pregnancy outcomes in women screened preconception for thyroid disease: an observational cohort study
Marie Fisk, University of Cambridge, To Investigate the Role of Specialized Pro-Resolving Mediators in Chronic Obstructive Pulmonary Disease.
Michael Flower, University College London, The DNA damage response in Huntington’s disease
Lucy Higgins, University of Manchester, To freeze or not to freeze? A growing dilemma.
Zoeb Jiwaji, University of Edinburgh, Single-cell transcriptomic analysis of the consequences of anaesthesia on neuronal and non-neuronal CNS cell populations.
Ashwini Oswal, University of Oxford, Probing replay in Parkinson's Disease
Samir Pathak, Bristol Medical School, Investigating risk factors for incisional hernia (IH): literature analysis and qualitative case studies to inform the design of a future cohort study
Stephen John Sammut, University of Cambridge, Ultrasensitive dynamic ctDNA detection to predict treatment response and resistance in women with early breast cancer.
Gavin Sewell, University of Cambridge, Deciphering the role of FAMIN in dendritic cell biology and chronic inflammation
Soha Sobhy, Queen Mary University of London, Developing a safety bundle to prevent postpartum haemorrhage in advanced labour caesarean section (C-Safe)
Andreas Themistocleous, University of Oxford, The use of microneurography to understand chronic neuropathic pain
Christopher Turnbull, University of Oxford, The feasibility of supplemental oxygen in patients with resistant hypertension and obstructive sleep apnoea
Andrew Michael Nicholas Walker, University of Leeds, Investigating the Role of the Insulin and Insulin-Like Growth Factor-1 Receptors in Vascular Aging
Matthew Butler, University of Bristol, Validating erythrocyte glycocalyx loss as an early predictor of diabetic vascular disease
Andrew Chapman, University of Edinburgh, Improving risk stratification and outcomes for patients with type 2 myocardial infraction
Adam Paul Croft, University of Birmingham, Functional diversity of fibroblast subsets in inflammatory arthritis: implications for disease pathology
Nicola Fletcher, University of Birmingham, Hepatitis E virus pathogenesis: Studies using in vitro and ex vivo models
James Gilchrist, University of Oxford, Host genetic determinants of rotavirus disease and immunity in African children
Upkar Gill, Queen Mary University of London, Evaluating on-treatment intrahepatic virus-host immune responses in chronic hepatitis B using fine needle aspirates.
Brian Halliday, Imperial College London, Using metabolomics as part of a precision medicine strategy to identify signatures of myocardial recovery
Nicholas Hamilton, University College London, The use of collagen embedded mesenchymal stem cells to enhance endogenous wound repair
Ciaran Hill, University College London, Understanding the effects of Wallerian degeneration on glioblastoma behaviour
Deena Iskander, Imperial College London, The role of the Erythroblastic Island in Diamond-Blackfan Anaemia
Michael Keogh, Newcastle University, Single-cell chromatin accessibility of the hippocampus in Alzheimer's disease
Andrew Lewis, University of Oxford, Hyperpolarized silicon nanoparticles for non-invasive molecular magnetic resonance imaging of the cardiovascular immune cell compartment
Lucia Li, Imperial College London, A multimodal assessment of the contribution of noradrenergic dysfunction to abnormal emotional processing after traumatic brain injury
Michael Marks, London School of Hygiene and Tropical Medicine, Understanding the spatial distribution and impact of scabies in urban environments in sub-Saharan Africa
Peter McColgan, University College London, CLEAR-HD: Cortical Layer Examination at high Resolution in Huntington's Disease
Gabriele Pollara, University College London, Trained immunity in the pathogenesis of tuberculosis
Tim Robinson, University of Bristol, Testing the use of extracellular vesicles to measure a stem cell gene expression signature in metastatic triple negative breast cancer
Aidan Roche, University of Edinburgh, Providing sensation to upper limb prostheses
Sarah Tansley, University of Bath, Establishing molecular differences in anti-TIF1γ epitopes in idiopathic inflammatory myopathy patients with and without malignancy
Mervyn Thomas, University of Leicester, Nonsense suppression therapy for infantile nystagmus - a pilot study
Umesh Vivekananda, University College London, Human single cell activity in epilepsy and cognition
Sarah Westbury, University of Bristol, Identification of novel loci in red cell disorders: combining data from rare diseases and population genetics.
Daniel Bromage, King's College London, Impact of Nrf2-mediated modulation of inflammation on remodelling after myocardial infraction
Vasileios Chortis, University of Birmingham, Mitochondrial serine metabolism targeting in adrenocortical carcinoma
Julia Colston, University of Oxford, Cytomegalovirus next generation sequencing and host immunobiology in immunosuppressed adult and paediatric cohorts
Abbe Crawford, Royal Veterinary College, Validating the use of deltaE50-MD dogs for modelling the cognitive, psychological and brain phenotype of Duchenne muscular dystrophy
Emma Culver, University of Oxford, The role of tissue fibroblasts in disease progression and organ involvement in IgG4-related disease
Dorothy Grogono, University of Cambridge, Understanding bacterial virulence in Mycobacterium abscessus pulmonary infection
Jenny Humphreys, University of Manchester, Juvenile Idiopathic Arthritis (JIA): occurrence, comorbidity and healthcare utilisation
Jan Idkowiak, University of Birmingham, Childhood Androgen Excess as a Forerunner of Metabolic Disease
Ahmad Khoder, Imperial College London, Characterisation of CD21-CD27- B cells and platelet specific autoimmune B cells in patients with immune thrombocytopenia
Yi Shiau Ng, Newcastle University, Understanding and Investigating Cerebellar Ataxia in Adult Mitochondrial Disease
Grace Okoli, Queen Mary University of London, Improving the process of CA125 testing in primary care for the early stage diagnosis of ovarian cancer, a mixed methods approach
Saoirse O'Toole, King's College London, Validation of platform for detecting pathological tooth wear in primary care
Stella-Maria Paddick, Newcastle University, HIV-associated neurocognitive disorders (HAND) in adults aged 50 and over attending a Government clinic in Northern Tanzania. A neuroimaging-supported study of phenotype, and pilot of alternative lower cost HAND biomarkers for low-resource settings.
Dimitris Papamargaritis, University of Leicester, The effect of Canagliflozin 300mg on glucose homeostasis in subjects without diabetes after bariatric surgery: A randomised, open-label, two period crossover study.
Ruth Payne, University of Sheffield, Analysis of innate immune responses following immunisation with a novel blood-stage Plasmodium falciparum vaccine using different vaccination regimes
Jason Powell, Newcastle University, Innate immune disruption caused by tracheostomy in infants
Michal Rolinski, University of Bristol, Tracking motoric progression in established and prodromal Parkinson's disease
Simon Sawhney, University of Aberdeen, Multicentre Acute kidney injury and Readmissions Replication Study (MARS)
Emma Searle, University of Manchester, Improving Outcomes in Elderly Patients with Myeloma through Targeting of the Tumour Microenvironment