The Raymond and Beverly Sackler Distinguished Lecture in the Medical Sciences 2006

00.00, Monday 27 November 2006

Cells have access to a very extensive Ca2+ signalling toolkit from which each cell type expresses a unique set of? components to create Ca2+ signalling systems with different spatial and temporal properties.

Such signalling systems are constantly being remodelled. A number of important disease states may result from abnormal remodelling of Ca2+ signalling systems. Congestive heart failure, a major cause of human morbidity and mortality, is controlled by a number of signalling pathways of which Ca2+ seems to play a prominent role.?

Calcium signalling in health and disease

Lecture delivered by Sir Michael J. Berridge FMedSci, Laboratory of Molecular Signalling, The Babraham Institute, Cambridge.

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