Dr Niharika A Duggal, University of Birmingham, Gut microbiome dysbiosis and immune ageing: investigating associations and potential for novel therapies.
Dr Scott Allen, University of Sheffield, Investigating how the MGO-NRF2 cellular protection pathway is affected in amyotrophic lateral sclerosis (ALS).
Dr Heather Bailey, University College London, Understanding the consequences of congenital cytomegalovirus infection: a feasibility study.
Dr Manuel Banzhaf, University of Birmingham, Creating a genome-wide mycobacterial stress-response map. (GCRF)
Dr Sarah Bath, University of Surrey, Is mild-to-moderate iodine deficiency in pregnancy a risk factor for hearing impairment in children?
Dr Megan Bergkessel, University of Dundee, Measuring activity dynamics in non-growing populations of bacteria.
Dr Valerie Brandt, University of Southampton, Investigating mechanisms of change and their neural underpinnings in patients with tic disorders receiving habit reversal training.
Dr Rochelle Burgess, University College London, Mapping patterns of risk and resilience to mental health consequences of child marriage in Zimbabwe (MARCH). (GCRF)
Dr Bernadette Carroll, University of Bristol, Spatial regulation of mTORC1 in Tuberous Sclerosis.
Dr Alan Cartmell, University of Liverpool, What features of bacterial carbohydrate sulfatases can be exploited for human health?
Dr Ines Cebola, Imperial College London, Investigation of NAFLD-associated epigenetic dysregulation.
Dr Liye Chen, University of Oxford, Investigating the functional basis of shared genetic risks across immune-mediated inflammatory diseases.
Dr Gemma Clarke, University of Leeds, Understanding access to palliative care by ethnic minority groups in the UK: with a focus on South Asians and those with refugee or asylum seeker status.
Dr Rebecca Coll, Queen's University Belfast, Investigating the regulation of the human NLRP3 inflammasome.
Dr James Connolly, Newcastle University, Deciphering the regulatory mechanisms underpinning niche-adaptation of pathogenic Escherichia coli during systemic infection.
Dr Anne Cori, Imperial College London, Developing reliable epidemic forecasting using branching processes: Ebola as a case study.
Dr Lauren Cowley, University of Bath, Novel machine learning models for real time pathogen management.
Dr David Doupe, Durham University, Stem Cell Derived Signals in Intestinal Stem Cell Homeostasis.
Dr Antonio Fernández Pardiñas, Cardiff University, PATRON - Pharmacogenomics of Antipsychotic Treatment and Response.
Dr Maria Filippetti, University of Essex, Understanding the developmental mechanisms underlying emotional eating.
Dr Taya Forde, University of Glasgow, A novel targeted sequencing approach for untangling the epidemiology of endemic anthrax, a neglected zoonosis. (GCRF)
Dr Rene Frank, University of Leeds, The in situ molecular architecture of Alzheimer’s disease pathology.
Dr Jennifer Greaves, Coventry University, Investigating the function and substrate interaction network of ABHD16A, a novel regulator of protein S-acylation.
Dr James Hall, University of Liverpool, Understanding the spread of multi-resistance megaplasmids in Pseudomonas.
Dr Sally Hargreaves, St George's University of London, Developing and testing an innovative multi-disease screening and catch-up vaccination tool to strengthen delivery systems to migrants in UK primary care.
Dr Musa Hassan, University of Edinburgh, Using single-cell dual RNA sequencing to interrogate host immunity to pathogens.
Dr Kristina Kirschner, University of Glasgow, What is the role of secondary senescence in disease? Elucidating the role of Notch signalling in secondary senescence.
Dr Efterpi Kostareli, Queen's University Belfast, Epigenetic effects of BTK inhibition in chronic lymphocytic leukaemia.
Dr Eneko Larrañeta, Queen's University Belfast, Intranasal implantable devices for prolonged drug delivery in schizophrenic patients.
Dr Bethan Lloyd-Lewis, University of Bristol, Deciphering the contribution of development and age to breast cancer aetiology
Dr Leeanne McGurk, University of Dundee, Defining novel therapeutic targets for TDP-43-associated neurodegenerative disease.
Dr Erik Mire, Cardiff University, Deciphering the interplay between maternal obesity and neuroimmune interactions during brain development.
Dr Síle Molloy, St George's University of London, Impact of combined oral therapy of fluconazole plus flucytosine for treatment of asymptomatic cryptococcal antigen positive patients in advanced HIV patients in Tanzania: A single arm intervention trial. (GCRF)
Dr Valentina Mosienko, University of Exeter, Novel mechanisms in depression: investigating the effects of astrocytic lactate on emotional behaviour.
Dr Ana Namburete, University of Oxford, Ultrasound-Based Assessment of Brain Folding Patterns in Early Pregnancy.
Dr Laura Nellums, University of Nottingham, EMERGE: Examining Migration and the Epidemiology of Resistance in Groups in Europe.
Dr Graham Norquay, University of Sheffield, Using hyperpolarised 129Xe MRI to evaluate tumour hypoxia in patients with lung cancer.
Dr Patricia P. Esteban, Aston University, A novel microfluidic co-culture platform to study functional responses of neuronal and glial cells ex vivo.
Dr Sebastian Pattinson, University of Cambridge, 3D Printing Imperceptible Orthoses with Biomimetic Geometry and Molecular Structure to Enable Healthy Gait.
Dr William Peveler, University of Glasgow, Fluorescent Sensor Arrays for Serum-Based Liver Fibrosis Detection.
Dr James Smith, University of East Anglia, Investigating cardiomyocyte communication in hypertrophic cardiomyopathy.
Dr Laura Southgate, St George's University of London, Characterisation of the cellular role of ATP13A3 and functional impact of variation underlying pulmonary arterial hypertension.
Dr Rachel Sparks, King's College London, Learning Movement Signatures from Video-Telemetry to Localize Epileptic Seizures.
Dr George Stothart, University of Bath, Developing functional biomarkers of early Alzheimer's disease.
Dr Clare-Louise Towse, University of Bradford, Role of isomerisation in cardiac amyloidosis.
Dr Patrick Walker, Imperial College London, Evaluation of the potential for rapid diagnostic testing for malaria within antenatal care to provide sustainable, dynamic and scalable malaria surveillance. (GCRF)
Dr Gernot Walko, University of Bath, Targeting YAP/TAZ as a novel therapeutic strategy in cutaneous squamous cell carcinoma.
Dr Helen Waller-Evans, Cardiff University, Developing an NPC1 activity assay using the novel fluorescent substrate AQ2 for use in basic research and drug discovery.
Dr Qian Wu, University of Leeds, Defining the structural mechanism of the cellular response to DNA interstrand crosslink lesions.
Dr Louise Atkinson, Queen's University Belfast, Exploiting CRISPR/Cas9 for the Control of Parasitic Nematode NTDs. (GCRF)
Dr Kirsty Bannister, King's College London, Defining descending modulatory pathways that regulate spinal nociceptive processing
Dr Samir Bhatt, Imperial College London, Unravelling and predicting the spatiotemporal structure of infectious disease outbreaks. (GCRF)
Dr Catalin Chimerel, University of Exeter, Measuring antibiotic permeation in single bacteria with absorption spectroscopy
Dr Owen Davies, Loughborough University, Deciphering molecular crosstalk in the musculoskeletal system: vesicle-mediated communication and its impact on bone health
Dr Maria Deprez, King's College London, Artificial intelligence to characterise abnormal brain development and neurocognitive disorders
Dr Athanasios Didangelos, University of Leicester, New proteomics and molecular approaches to study IgA Nephropathy
Dr Rebecca Drummond, University of Birmingham, Role and Control of the Functional Specialisation of Microglia during Fungal Meningitis
Dr Emanuele Giorgi, Lancaster Medical School, Spatio-temporal variation of malaria transmission in Africa: modelling, capacity-building and translating research into practice. (GCRF)
Dr Alice Giustacchini, University College London, Investigating the Implications of Stem Cell Metabolic Heterogeneity in Normal and Malignant Hematopoiesis
Dr Caroline Gorvin, University of Birmingham, Manipulating GPCR heterodimerisation for novel obesity and tumour therapies
Dr Stuart Greenhill, Aston University, Network Dynamics of Focal Cortical Dysplasia
Dr Gisela Helfer, University of Bradford, The role of hypothalamic tanycytes in the circadian control of energy metabolism
Dr Brian Hudson, University of Glasgow, Long Chain Fatty Acid Mediated Communication Between Metabolism and Inflammation as a Potential Therapeutic Target for Type 2 Diabetes
Dr Nicola Irwin, Queen's University Belfast, Responsive hydrogel platforms towards the prevention of urinary catheter infections and blockages
Dr Katherine Keenan, University of St Andrews, Social inequalities in chronic disease trajectories in mid and later life: taking account of multimorbidities. (GCRF)
Dr Johnathan Labbadia, University College London, Investigating the interplay between mitochondrial signalling and cytosolic protein homeostasis
Dr Jorn Lakowski, University of Southampton, Modelling retinitis pigmentosa associated cone photoreceptor death using stem cell derived organoids
Dr Paul Miller, University of Cambridge, Developing novel modulators of GABA-A receptors
Dr Luca Modenese, Imperial College London, Computational framework for patient-specific surgical planning of knee osteotomies
Dr Giovanna Nalesso, University of Surrey, Role of Calcium Calmodulin Kinase II in the modulation of lipid metabolism in the articular chondrocytes
Dr Dimitrios Papadopoulos, University of Edinburgh, Cell-to-cell variability in the concentration and chromatin-binding kinetics of pioneer transcription factors coordinate vertebrate development
Dr Christopher Rhodes, Imperial College London, Functional and epigenomic characterisation of genetic associations in pulmonary arterial hypertension
Dr James Robinson, University of Leeds, Defining the spatial requirements for therapeutic modulation of signaling through FcγRIIa
Dr Kevin Rouault-Pierre, Queen Mary University of London, Stress integration in normal and malignant haematopoietic stem cells
Dr Gabriele Schweikert, University of Dundee, Novel Machine Learning Techniques to Elucidate Function and Dynamics of Epigenomic Mechanisms
Dr Maria Secrier, University College London, Quantitative evaluation of gene dosage and genomic instability effects on metastatic transformation of solid cancers
Dr Tatyana Shelkovnikova, Cardiff University, Developing tools to monitor expression of lncRNA NEAT1 isoforms for basic research and drug discovery
Dr Mirre Simons, University of Sheffield, Mechanisms of age-dependent effects of reduced mTor signalling on life expectancy: towards short-term treatments for ageing-related disease
Dr Ana Tiganescu, University of Leeds, Regulation of skin function and wound healing by pre-receptor glucocorticoid metabolism in diabetes
Dr Jessica Tyrrell, University of Exeter, Using genetics to understand the complex relationships between obesity and depression in diverse global settings. (GCRF)
Dr Alessio Vagnoni, King's College London, Linking mitochondrial transport and function in ageing Drosophila neurons.
Dr Maarten Zwart, University of St Andrews, The circuit basis of descending motor control: fast whole-brain activity imaging at cellular resolution
Dr Dennis Wang, University of Sheffield, Evidencing subtypes of disorders with comorbidities through a consensus of clinical and multi-omic traits
Dr Shoba Amarnath, Newcastle University, The role of PD-1 in modulating ILC-2s in the tumour microenvironment
Dr Andrew Atkin, University of East Anglia, Age-related changes and determinants of physical activity, sedentary behaviour and sleep in young people
Dr Nicolas Barry, University of Bradford, Understanding the anticancer properties of metal-based drug candidates
Dr Akshay Bhinge, University of Exeter, Investigating the interactions of noncoding RNAs and aging pathways in driving motor neuron degeneration in ALS
Dr Lucy Bowes, University of Oxford, Adolescents at-risk of depression: examining the role of bullying as a causal risk factor using polygenic risk scores and virtual reality
Dr Ruth Bowness, University of St Andrews, Using individual-based mathematical models to study antibiotic resistance. (GCRF)
Dr Jonathan Cox, Aston University, Investigating the physiology of non-replicating persistent mycobacteria for latent tuberculosis drug discovery. (GCRF)
Dr Frank Dondelinger , University of Lancaster, Predicting clinical progression in biologically heterogeneous neurodegenerative diseases
Dr Maria Fragiadaki, University of Sheffield, Growth-hormone/STAT5 signalling in the polycystic kidney – using transcriptomics to unravel pathogenesis.
Dr Catherine Grainger, University of Stirling, Remembering to remember: What techniques can be used to improve prospective memory in individuals with autism spectrum disorder (ASD)?
Dr James Hewitson, University of York, Do helminth-induced antibodies restrain macrophages in type-2 immunity? (GCRF)
Dr Michelle Holland, King's College London, Developmental programming of ribosomal DNA epigenetics: what is the functional link to metabolic disease risk?
Dr David Hughes, University of St Andrews, Posttranslational control of our innate immune response: exploring a novel role for ISGylation.
Dr Asif Iqbal, University of Birmingham, Investigating the role of galectins in chronic inflammation associated with atherosclerosis
Dr Yi Jin, Cardiff University, A chemical biology approach to control sepsis. (GCRF)
Dr Diana Jurk, Newcastle University, How does cell senescence impact on the ageing brain?
Dr Paul Kasher, University of Manchester, Identifying novel molecular regulators of brain injury following intracerebral haemorrhage
Dr Jemma Kerns, University of Lancaster, How does gene and protein expression, of collagen, affect the chemical and material properties of osteoarthritic bone?
Dr Matthew Loxham, University of Southampton, Redox Balance and Ferroptosis – A New Mechanism Behind the Health Effects of Air Pollution?
Dr MaryAnn Noonan, University of Oxford, The development of goal-directed behaviour and the underlying neural architecture across adolescence
Dr Linda Oude Griep , Imperial College London, A systems approach to reveal complex metabolic relations of fruit and vegetable consumption on cardiovascular health
Dr Catherine Pashley, University of Leicester, When biomes meet: Characterisation of bacterial and fungal microbiota in the airways of people with asthma and the impact of antimicrobial agents.
Dr Lavinia Paternoster, University of Bristol, Identification of drug targets for atopic dermatitis through multi-omic data integration
Dr Danielle Paul, University of Bristol, Cryo-Electron microscopy of cardiac thin filaments: Heart disease on a molecular level
Dr Elena Rainero, University of Sheffield, Unravelling extracellular matrix endocytosis in breast cancer
Dr Emma Robinson, King's College London, What makes your mind unique? Tailoring brain network models to individuals to enhance predictions of neurological development and disease
Dr Sebastian van de Linde, University of Strathclyde, Tuneable photoswitches for chromatic aberration-free multicolour super-resolution imaging
Dr Kirsty Wan, University of Exeter, Genesis and control of ciliary beating: a new look at an ancient structure. (GCRF)
Dr Jun Wang, Queen Mary University of London, Characterisation of functional non-coding mutations in follicular lymphoma
Dr Sarah White, University College London, Strengths and weaknesses in non-verbal communication in autism
Dr Helge Wurdemann, University College London, Stiffness and position control for soft robotic devices suitable for colo-rectal surgery
Dr Giulia Zanetti, University College London , Visualising the role of TANGO1 in COPII-mediated procollagen transport by cryo-EM
Dr Kate Baker, University of Liverpool, Multi-species models of antimicrobial resistance emergence and persistence, developed from real world epidemics.
Dr Marcella Bassetto, Cardiff University, Novel therapeutic strategies to overcome opsin misfolding and aggregation in retinal blinding diseases.
Dr Tim Blower, Durham University, Regulating bacterial growth through toxin-antitoxin systems.
Dr Peter Cook, University of Manchester, Defining the key human innate immune cells that control anti-fungal immunity and inflammation.
Dr Laura Ferraiuolo, University of Sheffield, The involvement of exosomal RNA in astrocyte-mediated toxicity in motor neurone disease.
Dr Juan Fontana, University of Leeds, Elucidating the structure of previously inaccessible fusion intermediates of Influenza A Virus by cryo-electron microscopy.
Dr James Garnett, Queen Mary, University of London, A multidisciplinary approach to identify new antibacterial targets within biofilms.
Dr Katie Gillies, University of Aberdeen, Feedback matters: How should trial results be reported back to participants?
Dr Jamie Johnston, University of Leeds, Optical mapping of olfactory circuitry.
Dr Antreas Kalli, University of Leeds, Membrane transport proteins: Understanding the red cell Band 3 anion exchanger function.
Dr Peter Keating, University College London, Developmental impact of intermittent hearing loss on spatial hearing in noisy environments
Dr Tiziana Lembo, University of Glasgow, Understanding cultural, social and epidemiological drivers of human anthrax infection in rural African communities.
Dr David Llobet-Navas, Newcastle University, Control of somatic reprogramming by the microRNA cluster-424/503 during breast tumorigenesis and its relation with pregnancy.
Dr Christian Nielsen, Queen Mary University of London, Organic Bioelectronic Sensors for Epilepsy Diagnosis.
Dr Michael Okun, University of Leicester, How do individual neurons engage in resting-state infraslow dynamics of the cortex?
Dr Alice Pollitt, University of Reading, Impact of Podoplanin signalling complexes on the separation of the lymphatic and blood vasculatures in vivo.
Dr Andela Saric, University College London, Amyloid aggregation: Inhibition of self-replication and membrane-mediated control.
Dr Inez Schoenmakers, University of East Anglia, Does vitamin D supplementation have anabolic effects on the osteocyte and does it benefit the renal-bone axis?
Dr Amanda Sferruzzi-Perri, University of Cambridge, Materno-fetal resource allocation; altering placental endocrine function by IGF2.
Dr Yihua Wang, University of Southampton, The role of Factor inhibiting HIF (FIH) in the development of idiopathic pulmonary fibrosis (IPF)
Dr Anna Barnard, Imperial College London, Selective Helix-Mimetics as Tools in Malaria Research.
Dr Christos Bergeles, University College London, 3D In-Focus Endoscopic Imaging with Light-Field Cameras: Optomechatronics and Algorithms.
Dr Maike Bublitz, University of Oxford, Proton Transporting ATPases: Structural and Functional Studies of Fungal Proton Pumps.
Dr Angus Cameron, Queen Mary University of London, Defining the role of PKN2 in cancer-associated fibroblasts.
Dr Richard Chahwan, University of Exeter, Chromatin modifications in genomic stability, immune diversity, and tumorigenesis.
Dr Edwin Chen, University of Leeds, Role of CHD4 Helicase in Malignant Megakaryopoiesis.
Dr Mihaela Crisan, University of Edinburgh, Investigate the link between the two hematopoietic stem cell types: different origins, different niches or both?
Dr Molly Crockett, University of Oxford, Identifying risk factors for personality disorder using computational neuroimaging and ecological momentary assessment.
Dr Margaret Cunningham, University of Strathclyde, A multi-disciplinary approach to thrombin receptor research – A focus on the interrogation of the Proteinase-activated Receptor 4 (PAR4) interactome.
Dr Alice Davidson, University College London, Investigating TCF4 triplet-repeat-mediated pathogenic mechanisms associated with Fuchs endothelial corneal dystrophy (FECD), a visually devastating and common age-related disease.
Dr Emma Dempster, University of Exeter, Using functional epigenomics to dissect the molecular architecture of schizophrenia.
Dr Catherine Hall, University of Sussex, How does Apolipoprotein E4 affect brain oxygenation and blood flow?
Dr Sian Henson, Queen Mary University of London, Investigating the dynamics of senescent human T-cell trafficking.
Dr Daniel Horton, University of Surrey, Understanding constraints and drivers acting on viruses that cross species barriers, using rabies virus as a model.
Dr Benjamin Lehne, Imperial College London, A trans-ethnic gut microbiome study of insulin resistance.
Dr Florian Merkle, University of Cambridge, Regulation of human neurones that promote feeding
Dr Emily Noël, University of Sheffield, The second heart field and cardiac morphogenesis – using transcriptomics to unravel heart development.
Dr Paulo Ribeiro, Queen Mary University of London, The Interplay Between Polarity and Hippo Signalling in the Regulation of Tissue Growth.
Dr Samantha Terry, King's College London, Radiobiological assessment of radionuclides used for therapy; how can they be used effectively?