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Professor Frances Platt FMedSci

Job Title
Professor of Biochemistry and Pharmacology
Department
Department of Pharmacology
Institution
University of Oxford
Year elected
2011

Interests

Specialities

glyosphingdipids, lysosomal storage diseases, substrate reduction therapy

Section committee elected by

Physics, chemistry, biochemistry, structural biology, mathematics, informatics and engineering applied to biomedicine

Online Information

Lab Website

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Institute Website

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Frances Platt is Professor of Biochemistry and Pharmacology at the University of Oxford. She is an expert on glycosphinogolipids (GSL) and glycosphingolipid (GSL) lysosomal storage disorders. She pioneered the first pharmacological approach to treat these disorders. This led to the development of an approved drug for type 1 Gaucher disease. Miglustat was approved by the EMEA in 2002 and by the FDA in 2003 and is now in use worldwide as the first oral therapy for a lysosomal disorder. Her studies have shed light on the nature of GSL ligands presented by CD1d in the immune system that are recognised by iNKT cells.

 
 
 
 
 
 
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