Dominic Withers is Professor of Diabetes and Endocrinology at MRC Clinical Sciences Centre. He has made outstanding contributions to establishing the key role of insulin/insulin-like growth factor signalling (IIS) in mammalian physiology and in the pathophysiology of type 2 diabetes, obesity, and ageing. His studies have given key insights into the mechanisms by which caloric restriction regulates mammalian lifespan implicating AMP-activated protein kinase signalling. This work paves the way for therapeutic strategies to treat the diseases of ageing with currently available agents that act upon such signalling pathways.
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Professor Dominic Withers FMedSci
Professor of Diabetes and Endocrinology and Honorary Consultant in Diabetes and Endocrinology
Metabolic Signalling Group
Imperial College London
diabetes, endocrinology, biology of ageing, cell signalling, mammalian physiologySection committee elected by
Medical and veterinary specialties and paediatrics