Fellow

Jeremy Pearson is Professor of Vascular Biology at KCL. He has made fundamental contributions to our understanding of endothelial biology as it relates to a variety of disease processes. Early in his career he was involved in the description of the endothelial cell origin of prostacyclin and the calcium dependency of its synthesis. More recently his group have played an important part in demonstrating that arginine uptake is a regulatory step in nitric oxide synthesis by endothelial cells. His other major pioneering contribution has been the development of in vitro techniques for studying the interaction between leukocytes and the endothelium, knowledge of which is fundamental of our understanding of vascular disease. His recent demonstration of endothelial cell autoantibodies in systemic sclerosis and other vasculitic conditions promise a much greater depth of understanding about the vasculitic process, and he is a leader in the field of the study of the microcirculation. Professor Pearson has also played crucial leadership roles and is Associate Medical Director of the BHF