Magda Zernicka-Goetz has made pioneering contributions to our understanding of the development of the early mammalian embryo. She developed novel cell-labelling and time-lapse imaging techniques to generate a complete atlas of cell fate in the early mouse embryo. She complemented this by pioneering mRNAs microinjection into individual cells to identify key cell-fate genes. She was the first to demonstrate that RNAi was effective in mammalian cells. Her work highlighted the importance of the inter-relationship between cell polarity and gene expression in fate decisions. Recently, she developed an in vitro system to analyse development from the blastocyst through gastrulation. She discovered cytoplasmic movements in eggs that are predictive of successful development.
Fellow
Back to directory listingProfessor Magdalena Zernicka-Goetz FMedSci
Job Title
Professor of Mammalian Development and Stem Cell Biology
Department
Department of Physiology
Institution
University of Cambridge
Year elected
2013
Interests
Specialitiesearly development of the Mammalian embryo and cell fate decisions
Section committee elected byCellular and developmental biology, microbiology and immunology, genetics
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