Gregory Hannon is Royal Society Professor of Molecular Cancer Biology at Cancer Research UK. He has played a substantial role in the discovery of cyclin dependent kinase inhibitors and in linking these to tumorigenesis, investigating both their biological roles and biochemical mechanisms. |He contributed substantially to the current understanding of the mechanism of RNAi, including the discovery of Dicer and the content and mechanism of action of RISC. Professor Hannon always maintained an interest in technology and has developed a number of widely-used approaches. These include short hairpin RNAs, the production of oligonucleotide libraries by in situ synthesis, and genome-partitioning strategies.