Professor Derek Mann FMedSci

Derek Mann, Chair of Hepatology at Newcastle University, has made a series of discoveries that help describe mechanisms by which liver disease progresses to cirrhosis. He identified epigenetic processes controlling the fibrosis-promoting activities of liver myofibroblasts and led the discovery of angiotensin and serotonin pathways that become deranged in liver disease and translated this work to a clinical study on Losartan in fatty liver disease. Professor Mann’s leadership is demonstrated by 10 years directorship of the Newcastle Fibrosis Group which is considered world-leading. He was also previously Scientific Director of the Institute of Cellular Medicine and was recently appointed Dean of Research for the Faculty of Medicine at Newcastle.