Simon Lovestone is Professor of Old Age Psychiatry and Neuroscience at the Institute of Psychiatry, King’s College London. He has made significant contributions to several areas of Alzheimer’s disease research, particularly his work concerning the role of glycogen synthase kinase 3 which provides a potential route to novel therapeutic agents. Professor Lovestone has also worked on biomarkers for Alzheimer’s where he has shown that peripheral blood could provide useful biomarkers of disease. He has been a significant contributor to the UK-USA genetics collaboration that has made important discoveries in recent years in genetic susceptibility to Alzheimer’s. Besides these laboratory contributions he has also investigated the burden experienced by carers responsible for Alzheimer’s patients and the effects of pre-morbid personality on age of onset.