Laura Machesky is Senior Research Group Leader at the CRUK Beatson Institute in Glasgow. She discovered the 7-subunit Arp2/3 complex and during her early career demonstrated that this was a major regulator of actin dynamics and cell migration. This work changed the way the field understood fundamental principles of signalling to actin dynamics and impacted on biomedical problems such as host-pathogen interactions, endocytic trafficking, phagocytosis and cancer cell invasion. Dr Machesky’s group at the Beatson Institute has discovered how Rho GTPases control developmental migration of melanocytic cells, to better understand how these processes go wrong in melanoma metastasis.
Fellow
Back to directory listingProfessor Laura Machesky FRSE FMedSci
Job Title
Senior Research Group Leader
Department
CRUK Beatson Institute
Institution
University of Glasgow
Year elected
2016
Interests
SpecialitiesCell migration Cancer invasion and metastasis Actin dynamics and adhesion
Section committee elected byCellular and developmental biology, microbiology and immunology, genetics
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