Barry Potter is Professor of Biological and Medicinal Chemistry, and Head of Medicinal Chemistry, at the University of Bath. He has made wide-ranging contributions at the interface of Chemistry with both Biology and Medicine. In Chemical Biology he has elucidated the stereochemistry of numerous enzyme-catalysed phosphoryl and nucleotidyl transfer reactions using isotopically chiral substrates and DNA fragments. He has applied organic synthesis techniques in novel ways using carbohydrate, cyclitol and phosphorus chemistry to design modulators of cellular signal transduction processes that mobilizing intracellular Ca2+- second messengers. Of particular relevance to this Academy he has pioneered the novel aryl sulfamate pharmacophore in drug design. Unusually within an academic setting, he has brought compounds from initial academic concept to multiple clinical trials in women’s health. These have shown clear evidence of efficacy in humans, particularly in the anti-cancer field related to hormone-dependent breast cancer.
Fellow
Back to directory listingProfessor Barry Potter FMedSci
Job Title
Professor of Biological & Medicinal Chemistry
Department
Pharmacology
Institution
University of Oxford
Year elected
2008
Interests
Specialitiesmedicinal and biological chemistry, drug design, discovery and development, synthetic organic chemistry, chemistry of cellular signalling, cancer therapeutics
Section committee elected byPhysics, chemistry, biochemistry, structural biology, mathematical sciences including statistics, informatics, imaging and engineering applied to biomedicine
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