Professor Dorian Haskard is the British Heart Foundation’s Sir John McMichael Professor of Cardiovascular Medicine at Imperial College London. He has been at the forefront of research into the role of endothelium in inflammation for many years. He was amongst the first to study the molecular mechanisms by which cytokines modulate endothelial cell function. He made the first monoclonal antibodies reactive with E-selectin, ICAM-1 and VCAM-1, and has used his antibody to E-selectin to take his research from the laboratory to the clinic. He used monoclonal antibodies to E-selectin to target activated endothelium in vivo and showed that this could image activated endothelium in patients with inflammatory arthritis and inflammatory bowel disease.