Professor Tony Moore is the Duke Elder Professor of Ophthalmology at the Institute of Ophthalmology UCL. He is a distinguished clinician scientist and surgeon who has made major contributions in his work on inherited eye diseases. He has built and led collaborative teams of clinicians and basic scientists to probe clinical problems such as dominant optic atrophy. Families with this disorder were identified in the clinic, had detailed investigation of their phenotype and, following molecular genetic studies a novel gene was identified. He has major research programmes in two areas of retinal disease and in inherited cataract. His work on retinal dystrophies has identified genetic mutations underlying monogenic disorders and explored the effects of specific mutations on retinal function. With David Hunt he was the first to identify mutations in the retinal guanylate cyclase gene as a cause of Cone-Rod dystrophy and has identified a number of novel loci causing cone-rod and macular dystrophies. More recently he has established an MRC-funded programme between the Institute of Ophthalmology in London and Cambridge University to study the genetic epidemiology of age-related macular degeneration. Together with Professor Shomi Bhattacharya he has established a world leading programme on the molecular genetics of cataract. This team was the first to identify mutations in genes encoding connexin 46, connexin 50, aquaporin 0, and alpha B crystallin as a cause of inherited cataract. His work sits at the forefront of the field in each of the areas in which is involved, and yet he continues to run a busy clinical service and is committed to undergraduate and postgraduate teaching. He has attracted many high calibre young clinicians to work in this area of research and has continued to mentor them through their independent research careers. He is an inspirational clinical scientist and academic surgeon.