Andrew Tutt is Director of the Breast Cancer Now Research Centre at the Institute of Cancer Research. He is distinguished for seminal contributions to developing new therapies targeting aberrant DNA damage responses in breast and ovarian cancers. By combining his clinical experience with strong expertise in basic cancer biology, he has bridged the interface between these disciplines and driven rapid translation of fundamental discoveries. His scientific, clinical and communication skills, strategic leadership and relentless energy to explain and translate basic science for patient benefit have made him a highly valued colleague in the international guideline consensus and research steering groups.