Xin Lu’s work has been focused on the understanding of how to selectively activate the tumour suppressor p53 to kill cancer cells. She studied p53’s response to both oncogene activation and DNA damaging signals. She was also one of the first to illustrate how to selectively activate the tumour suppressor p53 to kill cancer cells through her pioneering discovery of the ASPP family of proteins. Her contribution has been ground-breaking and of enormous significance, as deregulation of this pathway is seen in developmental disorders and many cancers. The ASPP family of proteins serve as new biomarkers and excellent new targets for the development of novel cancer therapies.
Fellow
Back to directory listingProfessor Xin Lu FRS FMedSci
Job Title
Branch Director, Professor of Cancer Biology
Department
Ludwig Insitute for Cancer Research
Institution
University of Oxford
Year elected
2013
Interests
Specialitiescancer biology, tumour suppression, cell death, differentiation, cell growth, gene expression
Section committee elected byCellular and developmental biology, microbiology and immunology, genetics
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