Starter Grants for Clinical Lecturers

Daniel Bromage, King's College London, Impact of Nrf2-mediated modulation of inflammation on remodelling after myocardial infraction

Vasileios Chortis, University of Birmingham, Mitochondrial serine metabolism targeting in adrenocortical carcinoma

Julia Colston, University of Oxford, Cytomegalovirus next generation sequencing and host immunobiology in immunosuppressed adult and paediatric cohorts

Abbe Crawford, Royal Veterinary College, Validating the use of deltaE50-MD dogs for modelling the cognitive, psychological and brain phenotype of Duchenne muscular dystrophy

Emma Culver, University of Oxford, The role of tissue fibroblasts in disease progression and organ involvement in IgG4-related disease

Dorothy Grogono, University of Cambridge, Understanding bacterial virulence in Mycobacterium abscessus pulmonary infection

Jenny Humphreys, University of Manchester, Juvenile Idiopathic Arthritis (JIA): occurrence, comorbidity and healthcare utilisation

Jan Idkowiak, University of Birmingham, Childhood Androgen Excess as a Forerunner of Metabolic Disease

Ahmad Khoder, Imperial College London, Characterisation of CD21-CD27- B cells and platelet specific autoimmune B cells in patients with immune thrombocytopenia

Yi Shiau Ng, Newcastle University, Understanding and Investigating Cerebellar Ataxia in Adult Mitochondrial Disease

Grace Okoli, Queen Mary University of London, Improving the process of CA125 testing in primary care for the early stage diagnosis of ovarian cancer, a mixed methods approach

Saoirse O'Toole, King's College London, Validation of platform for detecting pathological tooth wear in primary care

Stella-Maria Paddick, Newcastle University, HIV-associated neurocognitive disorders (HAND) in adults aged 50 and over attending a Government clinic in Northern Tanzania.  A neuroimaging-supported study of phenotype, and pilot of alternative lower cost HAND biomarkers for low-resource settings.

Dimitris Papamargaritis, University of Leicester, The effect of Canagliflozin 300mg on glucose homeostasis in subjects without diabetes after bariatric surgery: A randomised, open-label, two period crossover study.

Ruth Payne, University of Sheffield, Analysis of innate immune responses following immunisation with a novel blood-stage Plasmodium falciparum vaccine using different vaccination regimes

Jason Powell, Newcastle University, Innate immune disruption caused by tracheostomy in infants

Michal Rolinski, University of Bristol, Tracking motoric progression in established and prodromal Parkinson's disease

Simon Sawhney, University of Aberdeen, Multicentre Acute kidney injury and Readmissions Replication Study (MARS)

Emma Searle, University of Manchester, Improving Outcomes in Elderly Patients with Myeloma through Targeting of the Tumour Microenvironment

Robindra Basu Roy, University of Oxford, Exploring mechanisms of paediatric immunity to M. tuberculosis infection in children

Malenka Bissell, University of Leeds, Improving patient selection for successful pulmonary artery stenting

Leonidas Chouliaras, University of Cambridge, A pilot study on neuron specific methylomic analysis in Dementia with Lewy Bodies

Michael Clynes, University of Southampton, Does epigenetic age acceleration predict future musculoskeletal outcomes?

Abhishek Das, London School of Hygiene and Tropical Medicine, Evaluation of a novel innate CXCL8+ effector T cell in neonatal bacterial infection

Karen Eley, University of Cambridge, Radiation and artefact free imaging in children with craniofacial abnormalities

David Erritzoe, Imperial College London, Validation of novel paradigms for multi-modality brain imaging in addiction research

Kezia Gaitskell, University of Oxford, The molecular pathological epidemiology of kidney cancer in the Million Women Study: A pilot study

Jenna Gregory, University of Edinburgh, Probing differential susceptibilities to extra-motor pathology in ALS

Josefine Hirschfeld, University of Birmingham, Developing a three-dimensional research model of neutrophil-mediated tissue destruction during inflammation

Catherine Houlihan, University College London, Undiagnosed viral central nervous system infections in Uganda; clinical insights from metagenomic analysis

Sasha Howard, Queen Mary University of London, Investigation of the genetic basis of disordered pubertal timing

Ben Jones, Imperial College London, Studying the impact of biased GLP-1 receptor signalling in humans

Muzaffer Kaser, University of Cambridge, Investigation of links between depression, cognition and inflammation in the Northern Finland Birth Cohort 1966

Evgeny Kushnerev, University of Manchester, Dental Pulp Stem Cells - investigations into methods of bone regeneration using 3D printed scaffold

Stephen Makin, University of Glasgow, Ultra highfield MRI in to detect thrombus in lacunar stroke

Helen Parry, University of Birmingham, Analysis of cellular immune function in patients with Chronic Lymphocytic Leukaemia who are undergoing therapy with novel therapeutic agents

Eva Carolina Pereira Mendes Serrao, University of Cambridge, Non-invasive diagnosis of hepatocellular cancer (HCC) lesions in liver transplant candidates using hyperpolarised [1-13C]pyruvate

Louise Porter, University of Liverpool, Investigate the anti-apoptotic effects of the differentially methylated gene in dry AMD FAIM2 (FAS apoptosis inhibitory molecule 2) in retinal pigment epithelium (RPE)

Vibhore Prasad, King's College London, Earlier identification of children and young people with attention-deficit/hyperactivity disorder (ADHD) using their medical records

Foad Rouhani, University of Cambridge, Investigating the safety profiles of differentiated human pluripotent stem cells

Fotios Sampaziotis, University of Cambridge, Characterization of cholangiocyte subpopulations and their role in repair and regeneration of the biliary tree

Gregory Scott, Imperial College London, Developing a measure of conscious level with electroencephalography and transcranial electrical stimulation

Anoop Shah, University of Edinburgh, Trends in the incidence of and outcomes following myocardial infarction

Sushma Shankar, University of Oxford, The use of cell-targeting nanotechnology to generate allospecific combination therapy with human T and B regulatory cells in transplantation

Hussein Al-Mossawi, University of Oxford, Single cell transcriptomic analysis of the T cell compartment in psoriatic arthritis

Nishkantha Arulkumaran, University College London, A New Antibacterial Route to Selectively Rupture Bacterial Membranes

Vian Azzu, University of Cambridge, The role of monocyte metabolism and signalling in non-alcoholic fatty liver disease

Mohammed Zaeem Cader, University of Cambridge, The role of FAMIN in controlling macrophage lipid biology and restricting inflammation

Johnathan Cooper-Knock, University of Sheffield, Characterisation of a novel genetic variant discovered by exome sequencing in familial amyotrophic lateral sclerosis

Felicity Fitzgerald, University College London, Carriage of antimicrobial resistant bacteria in children in Zimbabwe

Pankaj Garg, University of Sheffield, Whole heart, four-dimensional flow magnetic resonance imaging for accurate assessment of right and left heart flow haemodynamics

Alexandra Gilbert, University of Leeds, Developing predictive models of pelvic radiotherapy-related toxicity using patient reported outcomes

Rachel Guest, University of Edinburgh, Identifying novel genetic drivers of cholangiocarcinoma in primary sclerosing cholangitis

Melanie Hezzell, University of Bristol, Does surgical implantation of a novel bioprosthetic valved conduit in the right ventricular outflow tract affect right ventricular structure and function in healthy pigs?

Laura Jardine, Newcastle University, The evolution of clonal haematopoiesis in individuals with heterozygous GATA2 mutation

Simon Johnston, University of Nottingham, Effect of FoxA1 mutations on the transcriptional response to tamoxifen in lobular breast cancer

Paul Maciocia, University College London, A simple and non-genotoxic method to produce 'off the shelf' allogeneic chimeric antigen receptor T-cells

Barry Main, University of Bristol, Exploring strategies for implementing core information sets for informed consent to surgery for head and neck cancer: operationalising Montgomery

Thomas McKerrell, University of Cambridge, Single cell transcriptome profiling of mutant haematopoietic stem and progenitor cells (HSPCs) in patients with myeloproliferative neoplasms (MPN) enrolled in the TAMARIN clinical trial

Charlotte Pawlyn, Institute of Cancer Research, Developing 3D ex vivo models to study novel therapies targeting high-risk myeloma.

Michele Petruzzelli, University of Cambridge, Implicating the metabolic burden of anti-cancer immunity in cancer cachexia

Anvesha Singh, University of Leicester, Role of elastin in aortic remodelling in bicuspid and tricuspid aortic stenosis- a pilot metabolomics and MRI study

Carol Sinnott, University of Cambridge, Operational failures in general practice: An observational study of what general practitioners do and what gets in the way of doing it

Colin Steele, University of Glasgow, Characterising CXCR2 expressing neutrophils in colorectal liver metastases

Lisa Story, King's College London, MRI assessment of the cervix in non-pregnant women at risk of premature birth; a useful tool for assessment of cervical incompetence?  A pilot study

Mark Thomas, University of Birmingham, Impact of GPVI inhibition on fibrin-mediated platelet responses

Thomas Treibel, University College London, Comprehensive Myocardial Phenotyping in Aortic Stenosis

Timothy Walker, University of Oxford, Whole-genome sequencing M. tuberculosis in a remote, high burden setting

Yin Wu, University College London, Investigating the immune regulation of non-small cell lung cancer by gamma-delta T-cells

Kenny Yu, University of Manchester, Dissecting the heterogeneity of neuroinflammation in low grade and transforming astrocytomas using single cell RNAseq

Sarah Alderson, University of Leeds, An interrupted time series analysis of the Campaign to Reduce Opioid Prescribing

Marc Bailey, University of Leeds, Imaging pathological vascular remodelling in abdominal aortic aneurysm using [18F]Fluorothymidine

Harry Bulstrode, University of Cambridge, Studying gliomagenesis using defined mutations in primary human brain cells

Faye Cooles, Newcastle University, Early RA patient stratification by interferon gene signature – towards optimising clinical outcomes

Rebecca Hill, Newcastle University, Characterising and understanding the mutational landscape of relapsed medulloblastoma

Sarah Howles, University of Oxford, The role of High Mobility Group Nucleosomal Binding Protein 1 in the regulation of urinary calcium excretion.

Aadil Khan, Institute of Cancer Research, Elucidating the drivers of radiation fibrosis in normal tissues: a translational study of neoadjuvant breast radiotherapy and free flap reconstruction

Simon Lambden, University of Cambridge, The role of the pulmonary endothelial HIF isoforms in regulating systemic vascular function

Eileen Parkes, Queen’s University of Belfast, Investigating the immune response to neoadjuvant chemotherapy in breast cancer

Lucia Possamai, Imperial College London, Interactions between Kupffer cells and monocytes in sterile liver inflammation

Paul Ryan, Queen Mary University of London, Investigating phenotypic and functional heterogeneity in γδ T cells

Marietta Stadler, King’s College London, Exploring the barriers to a safe diabetes control in people with type 1 diabetes and eating disorders through better understanding of the psychological and physiological triggers leading to insulin omission

Victoria Stoll, University of Birmingham, Advanced Cardiovascular Magnetic Resonance Techniques to Identify Novel Imaging Biomarkers of Disease Progression and Therapeutic Response in Congenital Heart Disease

Kate Tatham, Imperial College London, The Role of the Lungs in Monocyte Dysfunction in Sepsis

Sofia Theodoropoulou, University of Bristol, The role of mast cells in the pathophysiology of age-related macular degeneration

Kate Walker, University of Nottingham, Childbirth experience questionnaire 2: validating its use in the United Kingdom

Steven Williams, King’s College London, A combined optical and electrogram mapping system to determine the impact of atrial remodelling on electrogram morphology

Tom Wingfield, University of Liverpool, END-TB: enhancing TB control by mitigating catastrophic costs of TB-affected households

Paolo Biancheri, University of East Anglia, Proteolytic degradation of anti-tumour necrosis factor (TNF)-alpha and anti-integrin agents: correlation with response to treatment in inflammatory bowel disease (IBD)

Delanjathan Devakumar, University College London, Long-term effects of the Indian Ocean tsunami in Sri Lankan adolescents

Jessica  Eccles, University of Sussex, Applying leading-edge multimodal neuroimaging and neural connectivity tools to characterise brain mechanisms that link joint hypermobility to anxiety

Amy Foulkes, University of Manchester, STRATOSPHERE: STRATification Of Systemic Psoriasis THERapiEs

Alex Gordon-Weeks, University of Oxford, Fibroblast Growth Factor Receptor Inhibition for Vascular Normalisation and Chemosensitisation

Adam Handel, University of Oxford, Identifying pathogenic T-cell clones in autoimmune demyelinating disease using single cell sequencing

George Harston, University of Oxford, 3D pH-weighted Imaging in Acute Ischaemic Stroke

Jennifer Haworth, University of Bristol, Mechanisms of oral Streptococcus-induced platelet activation

James Hunter, University of Oxford, The effect of Normothermic machine perfusion of kidneys on mitochondrial function

Ivan Koychev, University of Oxford, Indoor and outdoor spatial navigation as a potential biomarker of preclinical Alzheimer's Disease

Oliver Lyons, King's College London, Endothelial patterning in venous valve development

Angus Macleod, University of Aberdeen, Individual-patient-data meta-analysis of prognostic studies in Parkinson's disease

Filipe Martins, University of Cambridge, PTEN expression as a biomarker for targeted therapies in high-grade serous ovarian cancer (HGSOC)

Georgios Oikonomou, University of Liverpool, Using genomics to prevent lameness-causing foot lesions in dairy cattle

Meghan Perry, University of Edinburgh, The use of metagenomics of hospital sewage as an AMR surveillance tool

Ricardo Petraco, Imperial College London, Real-time derivation of coronary pressure-flow slopes and development of novel, stenosis-specific and flow-independent parameters of stenosis severity: towards the application of invasive physiology in unstable haemodynamic conditions

Owen Pickrell, Swansea University, Using natural language processing software to enrich routinely collected electronic data for epilepsy research.

Lynne Sykes, Imperial College London, The interaction between gut microbiota, the systemic immune response and the risk of preterm labour

Karin Tuschl, University College London, Dissecting the mechanisms of manganese dyshomeostasis in disorders of manganese transport

Emma Wall, University College London, Identifying determinants of poor outcome in adult Streptococcus pneumoniae meningitis by transcriptional profiling

Michelle Williams, University of Edinburgh, Combined magnetic resonance coronary angiography and positron emission tomography in patients with coronary artery disease

Tim Williams, University of Cambridge, The role and utility of urinary exosomes in individuals with renal and urinary tract disorders

Kanmin Xue, University of Oxford, Enhancement of dual vector gene therapy for Stargardt disease through