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Professor Joyce Taylor-Papadimitriou FMedSci

Job Title
Senior Fellow/Visiting Professor
Department
Breast Cancer Biology Group
Institution
King's College London
Year elected
2001

Interests

Specialities

cancer immunology; cell and molecular biology of breast cancer

Section committee elected by

Genetics, cellular and developmental biology, microbiology and immunology

Professor Joyce Taylor-Papadimitriou is Principal Scientist and Joint Head of the ICRF Breast Cancer Biology Group at Guy’s Hospital. She is distinguished by her work defining the phenotypes of the malignant cell in breast cancer. In particular, she identified and characterised a tumour associated antigen (the MUC1 membrane mucin) as being a component of normal glandular epithelial cells that is over-expressed and aberrantly glycosylated in breast and other cancers such as ovarian cancer. This discovery has had a major impact in clinical oncology and glycobiology. The first antibody to the mucin which she developed has been shown in a Phase 1/11 trial to improve survival of ovarian cancer patients, and is being evaluated in a large randomised Phase 11 Trial. Immunogens based on the MUC1 mucin are also in clinical trial.

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